শুক্রবার, ৮ মার্চ, ২০১৩

Boehner says book accusations are baseless

This photo taken March 7, 2013 shows House Speaker John Boehner of Ohio meeting with reporters on Capitol Hill in Washington. Boehner says former Republican colleague Bob Ney is a disgraced congressman who went to jail and that Ney's criticisms of Boehner in a new book are "baseless and false."Boehner was asked at a news conference Thursday about Ney's reported accusations in his book that Boehner was more interested in playing golf and drinking than making policy and that in 2006 Boehner had reneged on a promise to get him a job if Ney left Congress. Boehner says Ney is making false statements in order to sell his book. Boehner said, quote, "It's sad." Like Boehner, Ney is an Ohio Republican. Ney spent 11 months in prison for his involvement in the Jack Abramoff lobbying scandal. (AP Photo/J. Scott Applewhite)

This photo taken March 7, 2013 shows House Speaker John Boehner of Ohio meeting with reporters on Capitol Hill in Washington. Boehner says former Republican colleague Bob Ney is a disgraced congressman who went to jail and that Ney's criticisms of Boehner in a new book are "baseless and false."Boehner was asked at a news conference Thursday about Ney's reported accusations in his book that Boehner was more interested in playing golf and drinking than making policy and that in 2006 Boehner had reneged on a promise to get him a job if Ney left Congress. Boehner says Ney is making false statements in order to sell his book. Boehner said, quote, "It's sad." Like Boehner, Ney is an Ohio Republican. Ney spent 11 months in prison for his involvement in the Jack Abramoff lobbying scandal. (AP Photo/J. Scott Applewhite)

FILE - In this Jan. 19, 2007 file photo, former Ohio Rep. Bob Ney arrives at U.S. Federal Court in Washington. House Speaker John Boehner says Ney is a disgraced congressman who went to jail and that Ney's criticisms of Boehner in a new book are "baseless and false."Boehner was asked at a news conference Thursday about Ney's reported accusations in his book that Boehner was more interested in playing golf and drinking than making policy and that in 2006 Boehner had reneged on a promise to get him a job if Ney left Congress. Boehner says Ney is making false statements in order to sell his book. Boehner said, quote, "It's sad." Like Boehner, Ney is an Ohio Republican. Ney spent 11 months in prison for his involvement in the Jack Abramoff lobbying scandal. (AP Photo/Pablo Martinez Monsivais, File)

(AP) ? House Speaker John Boehner says former Republican colleague Bob Ney is a disgraced congressman who went to jail and that Ney's criticisms of Boehner in a new book are "baseless and false."

Boehner was asked at a news conference Thursday about Ney's reported accusations in his book that Boehner was more interested in playing golf and drinking than making policy and that in 2006 Boehner had reneged on a promise to get him a job if Ney left Congress. Boehner says Ney is making false statements in order to sell his book. Boehner said, quote, "It's sad."

Like Boehner, Ney is an Ohio Republican. Ney spent 11 months in prison for his involvement in the Jack Abramoff lobbying scandal.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-03-07-Boehner-Ney/id-8b9e886c31354cf6abd4b055303e1a20

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Human Y chromosome much older than previously thought

Wednesday, March 6, 2013

UA geneticists have discovered the oldest known genetic branch of the human Y chromosome ? the hereditary factor determining male sex.

The new divergent lineage, which was found in an individual who submitted his DNA to Family Tree DNA, a company specializing in DNA analysis to trace family roots, branched from the Y chromosome tree before the first appearance of anatomically modern humans in the fossil record.

"Our analysis indicates this lineage diverged from previously known Y chromosomes about 300,000 ago, a time when anatomically modern humans had not yet evolved," said Michael Hammer, an associate professor in the University of Arizona's department of ecology and evolutionary biology and a research scientist at the UA's Arizona Research Labs. "This pushes back the time the last common Y chromosome ancestor lived by almost 70 percent."

Unlike the other human chromosomes, the majority of the Y chromosome does not exchange genetic material with other chromosomes, which makes it simpler to trace ancestral relationships among contemporary lineages. If two Y chromosomes carry the same mutation, it is because they share a common paternal ancestor at some point in the past. The more mutations that differ between two Y chromosomes the farther back in time the common ancestor lived.

Originally, a DNA sample obtained from an African American living in South Carolina was submitted to the National Geographic Genographic Project. When none of the genetic markers used to assign lineages to known Y chromosome groupings were found, the DNA sample was sent to Family Tree DNA for sequencing. Fernando Mendez, a postdoctoral researcher in Hammer's lab, led the effort to analyze the DNA sequence, which included more than 240,000 base pairs of the Y chromosome.

Hammer said "the most striking feature of this research is that a consumer genetic testing company identified a lineage that didn't fit anywhere on the existing Y chromosome tree, even though the tree had been constructed based on perhaps a half-million individuals or more. Nobody expected to find anything like this."

About 300,000 years ago falls around the time the Neanderthals are believed to have split from the ancestral human lineage. It was not until more than 100,000 years later that anatomically modern humans appear in the fossil record. They differ from the more archaic forms by a more lightly built skeleton, a smaller face tucked under a high forehead, the absence of a cranial ridge and smaller chins.

Hammer said the newly discovered Y chromosome variation is extremely rare. Through large database searches, his team eventually was able to find a similar chromosome in the Mbo, a population living in a tiny area of western Cameroon in sub-Saharan Africa.

"This was surprising because previously the most diverged branches of the Y chromosome were found in traditional hunter-gatherer populations such as Pygmies and the click-speaking KhoeSan, who are considered to be the most diverged human populations living today."

"Instead, the sample matched the Y chromosome DNA of 11 men, who all came from a very small region of western Cameroon," Hammer said. "And the sequences of those individuals are variable, so it's not like they all descended from the same grandfather."

Hammer cautions against popular concepts of "mitochondrial Eve" or "Y chromosome Adam" that suggest all of humankind descended from exactly one pair of humans that lived at a certain point in human evolution.

"There has been too much emphasis on this in the past," he said. "It is a misconception that the genealogy of a single genetic region reflects population divergence. Instead, our results suggest that there are pockets of genetically isolated communities that together preserve a great deal of human diversity."

Still, Hammer said, "It is likely that other divergent lineages will be found, whether in Africa or among African-Americans in the U.S. and that some of these may further increase the age of the Y chromosome tree."

He added: "There has been a lot of hype with people trying to trace their Y chromosome to different tribes, but this individual from South Carolina can say he did it."

###

The results are published in the American Journal of Human Genetics: http://www.cell.com/AJHG/abstract/S0002-9297(13)00073-6

University of Arizona: http://uanews.org

Thanks to University of Arizona for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127163/Human_Y_chromosome_much_older_than_previously_thought

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বৃহস্পতিবার, ৭ মার্চ, ২০১৩

Apple Will Miss Its Own Revenue Guidance, Says Citi - Business ...

Beck Diefenbach, Reuters

?

Citigroup has a new, quite bearish note on Apple this morning.

We ran through the meat of the note already. In a nutshell, demand for iPads and iPhones is falling, says Citi after talking to supply chain sources.

As a result, Citi cut its estimates. And the result of those estimate cuts is quite dire.

Citi is now calling for $40.45 billion in sales for the March quarter. Apple guided to between $41 and $43 billion in sales for this quarter. If Citi's forecast is accurate, then Apple would miss its own revenue guidance.

Apple has been missing analyst expectations lately, but we can't remember it ever missing its own guidance.

Source: http://www.businessinsider.com/apple-will-miss-its-own-revenue-guidance-says-citi-2013-3

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New films test if Land of Oz still paved with gold

LONDON (Reuters) - The entertainment industry has long viewed The Land of Oz as a road paved with gold, and two major new movie projects will test the public's appetite for yet more spin-offs from L. Frank Baum's novel published 113 years ago.

Not every project based on the American author's adventures in Oz has been a hit - even with Michael Jackson as Scarecrow, the 1978 adaptation "The Wiz" suffered poor reviews.

But the award-winning, record-breaking musical "Wicked", now in its 10th year, may have emboldened studios to revisit one of the world's most popular and lucrative fantasy properties.

"I don't think we're in danger of tiring of Oz," said Rhidian Davis, program manager at the British Film Institute, which is hosting a big retrospective of Oz-related cinema running at its Southbank home in London from March 1-14.

"One of the reasons for this success is the way in which children come to power, children topple adult figures in their world - Dorothy dispatches the Wicked Witch with a bucket of water," he said of the lasting Oz phenomenon.

"It's terrifically empowering in a way for children to think you can change things."

The first test comes on Friday with the theatrical release of Disney's 3D adventure "Oz the Great and Powerful", which reportedly cost $300-325 million to make and market and has been described by the New York Times as a "breathtaking gamble".

A lavish prequel to the original story, the movie stars James Franco in unfamiliar blockbuster territory as the wizard, after more familiar stars Robert Downey Jr. and Johnny Depp dropped out of the project, according to Hollywood trade press.

Industry estimates predict a hefty North American box office opening weekend of $65-75 million for the picture, directed by Sam Raimi. But experts also doubt it will have the staying power to match Disney's similarly-pitched 2010 hit "Alice in Wonderland" which enjoyed global ticket sales of $1 billion.

ANIMATION ADAPTATION NEXT UP

Next up may be 3D animation movie "Dorothy of Oz", which is near completion and due to hit theatres late in 2013 or early in 2014, according to producer Ryan Carroll.

With production costs of more than $60 million, it is a mid-level project by Hollywood standards but one that could help put Oz on the map for the digital age through mobile apps, video games and virtual worlds.

"This is an ideal time to revisit something of this creative nature and bring it up to date," Carroll said of the long-term project from Summertime Entertainment.

"Licensing and merchandising and the ongoing creation of games will be a big part of it," he told Reuters. "Today entertainment takes on more than just watching a movie - we're creating a virtual world, apps, a whole environment."

Summertime is basing the first movie of what it hopes will be a long-running Oz franchise on a novel by Roger Baum, L. Frank Baum's great-grandson who produced a series of spinoffs.

As in "Oz the Great and Powerful", there has been a tendency for movie adaptations to steer away from the 1900 Baum novel "The Wonderful Wizard of Oz" as source material even though it is in the public domain.

That is because the 1939 adaptation, starring Judy Garland as Dorothy in the most famous and successful of all Oz films, still has such a passionate following, while several elements, including the ruby slippers, are still guarded copyrights.

"We're already in development of the second (movie) project and have a total of 10 stories to draw from," Carroll explained of the deliberate move away from the original novel.

"What we have are unique intellectual properties not in the public domain. We have unique characters owned solely by us."

He is hoping that "Dorothy of Oz", with "Glee" star Lea Michele voicing the title role and Patrick Stewart, Dan Aykroyd and James Belushi among the cast, will be ready for a big global media splash at the Cannes film festival in May.

"The Wonderful Wizard of Oz" was a hit almost from the word go, and had already been turned into a stage play by 1902.

Due to popular demand, Baum had returned to Oz more than a dozen times in print by the time of his death in 1919, and co-founded one of the first film studios in Los Angeles that produced three feature-length Oz films in its short life.

In 1939 came MGM's "The Wizard of Oz", one of the most elaborate productions to come out of Hollywood and which, according to the U.S. Library of Congress, is the most-watched film of all time.

(Editing by Sonya Hepinstall)

Source: http://news.yahoo.com/films-test-land-oz-still-paved-gold-165604835--finance.html

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বুধবার, ৬ মার্চ, ২০১৩

Why space glitches aren't hurting SpaceX

Chris Hadfield / CSA / NASA via Twitter

SpaceX's Dragon cargo capsule is held by the International Space Station's Canadian-built robotic arm in advance of its berthing on Sunday. "A Dragon, snared and tamed," Canadian astronaut Chris Hadfield wrote on Twitter.

By Alan Boyle, Science Editor, NBC News

The commercial SpaceX rocket venture has launched Dragon cargo capsules to the International Space Station three times in the past year, and every time there's been a problem. Should NASA be upset?

Not really.

The fact that glitches have cropped up ? and have been solved, with no impact on the multimillion-dollar cargo resupply missions ? isn't a black mark against the California-based company. Rather, it's a sign that the designs for SpaceX's Dragon capsule and Falcon 9 are resilient in the face of the inevitable glitches associated with spaceflight. It's also a sign of things to come.


"We may see more mission aborts, where the cost of a mission may be a fraction of the cost of a 'perfect' spacecraft," says James Oberg, NBC News' space analyst. "For the same cost, you could launch three or four, or even eight or 10 'not-perfect' vehicles, with a success rate of 90 to 95 percent. and as a result, for the same starting cost launch many times more missions."

Rand Simberg, a former rocket engineer who now writes about spaceflight for a variety of publications, made a similar point in a PJMedia piece touting SpaceX's latest "successful failure": a problem with the Dragon's thruster system that was resolved when SpaceX's engineers issued commands to cycle the system's valves and clear out the lines with a blast of pressurized gas.

"It was a valuable failure in that it identified a potential problem with either the design or operations but didn't cost them the mission," Simberg wrote. After the system reset, the Dragon's thrusters performed without a hitch. The capsule was brought in for its berthing at the space station on Sunday, just a day later than originally scheduled.

"They did everything exactly right about the vehicle," Bill Gerstenmaier, NASA's associate administrator for human exploration and operations, told reporters after the thruster system was fixed.?

The snags that cropped up during the previous two Dragon launches were similarly resolved without major consequences for SpaceX or NASA:

  • Last May, SpaceX's Falcon 9 rocket lit up its engines for launch, but immediately shut them down when the flight computer detected an excessive pressure reading in one of the engines. Engineers found and fixed a problem with the engine's turbopump valve, and a few days later, the Falcon 9 launched the Dragon on a historic demonstration mission to the space station. In August, a NASA panel said it was satisfied with SpaceX's handling of the glitch and its aftermath.
  • Last October, one of the nine engines on the Falcon 9's first stage shut down during the ascent, due to a flaw in the sheathing that surrounded the engine. The other engines automatically adjusted their thrust to make up for the shutdown, and the Dragon successfully reached orbit. However, the Falcon wasn't able to put an Orbcomm telecommunications satellite that was carried as a secondary payload in its proper orbit. As a result, the satellite was lost. SpaceX President Gwynne Shotwell said the company tracked down the problem and beefed up its procedure for non-destructive evaluation of the Merlin rocket engines. Since the satellite loss, Orbcomm and SpaceX have renegotiated their launch contract.

SpaceX's communication director, Christina Ra, told NBC News that there the investigation of last week's thruster problem has already begun. "But I am hesitant to give you any commitment on whether or not we can give more detail, and what the timing would be," she wrote in an email, "because it does take time, the information is shared with and approved by multiple parties, and at the end of the day, regulated by ITAR."

That last acronym refers to the International Trade in Arms Regulations, which strictly limit the transfer of aerospace technology to foreign countries. SpaceX fears that the unauthorized disclosure of information about a rocket anomaly would get the company in ITAR trouble with the federal government, and maybe even get someone put in jail. "I don't look good in horizontal stripes," Shotwell joked.

Dealing with anomalies may well be a more frequent option for future spaceflight, even when humans are involved. Oberg noted that the subject came up when millionaire Dennis Tito was discussing his plan to send private-sector astronauts on a 501-day trip past Mars in 2018. "He described how his two-human crew to Mars would be occupied servicing, repairing and coaxing their life support systems, which would be designed to be fixable, not to be 'perfect,'" Oberg said in an email.

This is why SpaceX and NASA's other commercial partners are devoting so much attention to the development of launch abort systems for crew-capable spaceships. Those systems might actually have to be used someday.

"With a commercialized crew taxi that doesn't 'overspend' on unattainable perfect reliability, but accepts the occasional mission failure, you'll fly many more successful missions. You don't have to pay for it in crew safety, just in mission completion rates. And the high flight rates can shake out hardware to enhance reliability far more than flying a vehicle once or twice?a year, as with space shuttles." Oberg said.

"If there isn't a commercial crew mission abort at some point in the first 10 missions, I'd suspect they spent too much on reliability. I'm not talking about somebody getting hurt ? we need to build robust and reliable escape systems ? but just having to come home without accomplishing the purpose of the launch."

Does that sound scary? It shouldn't. The key to success in space may well be to make sure failure is an option that can be dealt with?? as SpaceX demonstrated last week.

March 1: The SpaceX Dragon cargo capsule's arrival at the International Space Station was delayed due to a problem with its thrusters. NBC's Tom Costello reports.

More about commercial space ventures:


Alan Boyle is NBCNews.com's science editor. Connect with the Cosmic Log community by "liking" the log's?Facebook page, following?@b0yle on Twitter?and adding the?Cosmic Log page?to your Google+ presence. To keep up with Cosmic Log as well as NBCNews.com's other stories about science and space, sign up for the Tech & Science newsletter, delivered to your email in-box every weekday. You can also check out?"The Case for Pluto,"?my book about the controversial dwarf planet and the search for new worlds.

Source: http://cosmiclog.nbcnews.com/_news/2013/03/06/17201079-why-its-good-for-spacexs-private-spaceships-to-rise-above-the-glitches?lite

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Fotos da passagem de som dos Jonas Brothers em Curitiba

5/03 Fotos da passagem de som dos Jonas Brothers em Curitiba


Fotos da passagem de som dos Jonas Brothers em Curitiba
Postado por: Camila Campos 5 Mar 2013

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Japan's regulators: "several steps" before approving 787 battery fix

Researchers say they know how the Hindenburg airship came to its fiery end: static electricity. Seventy-six years ago, the German dirigible was promoted as the future of trans-Atlantic flight, but instead it became the notorious poster child of air disasters. As the hydrogen-filled blimp was landing in Lakehurst, N.J., on May 6, 1937, it suddenly [...]

Source: http://news.yahoo.com/japans-regulators-several-steps-approving-787-battery-fix-052500189--finance.html

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